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CCR7 defines a precursor for murine iNKT cells in thymus and periphery

The precise steps of iNKT subset differentiation in the thymus and periphery have been controversial. We demonstrate here that the small proportion of thymic iNKT and mucosal associated invariant T cells that express CCR7 represent a multi-potent progenitor pool that gives rise to effector subsets w...

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Detalles Bibliográficos
Autores principales: Wang, Haiguang, Hogquist, Kristin A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115192/
https://www.ncbi.nlm.nih.gov/pubmed/30102153
http://dx.doi.org/10.7554/eLife.34793