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Tricyclic antidepressant amitriptyline inhibits 5-hydroxytryptamine 3 receptor currents in NCB-20 cells

Amitriptyline, a tricyclic antidepressant, is commonly used to treat depression and neuropathic pain, but its mechanism is still unclear. We tested the effect of amitriptyline on 5-hydroxytryptamine 3 (5-HT(3)) receptor currents and studied its blocking mechanism because the clinical applications of...

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Detalles Bibliográficos
Autores principales: Park, Yong Soo, Myeong, Seok Ho, Kim, In-Beom, Sung, Ki-Wug
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115347/
https://www.ncbi.nlm.nih.gov/pubmed/30181705
http://dx.doi.org/10.4196/kjpp.2018.22.5.585