Inhibition of voltage-dependent K(+) current in rabbit coronary arterial smooth muscle cells by the class Ic antiarrhythmic drug propafenone

In this study, we demonstrated the inhibitory effect of the Class Ic antiarrhythmic agent propafenone on voltage-dependent K(+) (Kv) channels using freshly isolated coronary artery smooth muscle cells from rabbits. The Kv current amplitude was progressively inhibited by propafenone in a dose-depende...

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Detalles Bibliográficos
Autores principales: An, Jin Ryeol, Li, Hongliang, Seo, Mi Seon, Park, Won Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115351/
https://www.ncbi.nlm.nih.gov/pubmed/30181706
http://dx.doi.org/10.4196/kjpp.2018.22.5.597

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115351/
https://www.ncbi.nlm.nih.gov/pubmed/30181706
http://dx.doi.org/10.4196/kjpp.2018.22.5.597

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