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Inhibition of voltage-dependent K(+) current in rabbit coronary arterial smooth muscle cells by the class Ic antiarrhythmic drug propafenone
In this study, we demonstrated the inhibitory effect of the Class Ic antiarrhythmic agent propafenone on voltage-dependent K(+) (Kv) channels using freshly isolated coronary artery smooth muscle cells from rabbits. The Kv current amplitude was progressively inhibited by propafenone in a dose-depende...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Korean Physiological Society and The Korean Society of Pharmacology
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115351/ https://www.ncbi.nlm.nih.gov/pubmed/30181706 http://dx.doi.org/10.4196/kjpp.2018.22.5.597 |