PDI-mediated S-nitrosylation of DRP1 facilitates DRP1-S616 phosphorylation and mitochondrial fission in CA1 neurons

Dynamin-related protein 1 (DRP1) is a key molecule to regulate mitochondrial fission. DRP1 activity is modulated by phosphorylation and S-nitrosylation on serine and cysteine residues, respectively. However, it is still unexplored whether S-nitrosylation of DRP1 affects its phosphorylation. In the p...

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Detalles Bibliográficos
Autores principales: Lee, Duk-shin, Kim, Ji-Eun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115394/
https://www.ncbi.nlm.nih.gov/pubmed/30158524
http://dx.doi.org/10.1038/s41419-018-0910-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115394/
https://www.ncbi.nlm.nih.gov/pubmed/30158524
http://dx.doi.org/10.1038/s41419-018-0910-5

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