Rab37 mediates exocytosis of secreted frizzled-related protein 1 to inhibit Wnt signaling and thus suppress lung cancer stemness

Recent studies have revealed that dysregulated Rab small GTPase-mediated vesicle trafficking pathways are associated with cancer progression. However, whether any of the Rabs plays a suppressor role in cancer stemness is least explored. Rab37 has been postulated as a tumor suppressive small GTPase f...

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Detalles Bibliográficos
Autores principales: Cho, Shu-Huei, Kuo, I-Ying, Lu, Pei-Jung Frank, Tzeng, Hong-Tai, Lai, Wu-Wei, Su, Wu-Chou, Wang, Yi-Ching
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115395/
https://www.ncbi.nlm.nih.gov/pubmed/30158579
http://dx.doi.org/10.1038/s41419-018-0915-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115395/
https://www.ncbi.nlm.nih.gov/pubmed/30158579
http://dx.doi.org/10.1038/s41419-018-0915-0

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