EMT- and stroma-related gene expression and resistance to PD-1 blockade in urothelial cancer

Cancers infiltrated with T-cells are associated with a higher likelihood of response to PD-1/PD-L1 blockade. Counterintuitively, a correlation between epithelial–mesenchymal transition (EMT)-related gene expression and T-cell infiltration has been observed across tumor types. Here we demonstrate, us...

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Detalles Bibliográficos
Autores principales: Wang, Li, Saci, Abdel, Szabo, Peter M., Chasalow, Scott D., Castillo-Martin, Mireia, Domingo-Domenech, Josep, Siefker-Radtke, Arlene, Sharma, Padmanee, Sfakianos, John P., Gong, Yixuan, Dominguez-Andres, Ana, Oh, William K., Mulholland, David, Azrilevich, Alex, Hu, Liangyuan, Cordon-Cardo, Carlos, Salmon, Hélène, Bhardwaj, Nina, Zhu, Jun, Galsky, Matthew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115401/
https://www.ncbi.nlm.nih.gov/pubmed/30158554
http://dx.doi.org/10.1038/s41467-018-05992-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115401/
https://www.ncbi.nlm.nih.gov/pubmed/30158554
http://dx.doi.org/10.1038/s41467-018-05992-x

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