Solution structures of multiple G-quadruplex complexes induced by a platinum(II)-based tripod reveal dynamic binding

DNA G-quadruplexes are not only attractive drug targets for cancer therapeutics, but also have important applications in supramolecular assembly. Here, we report a platinum(II)-based tripod (Pt-tripod) specifically binds the biological relevant hybrid-1 human telomeric G-quadruplex (Tel26), and stro...

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Detalles Bibliográficos
Autores principales: Liu, Wenting, Zhong, Yi-Fang, Liu, Liu-Yi, Shen, Chu-Tong, Zeng, Wenjuan, Wang, Fuyi, Yang, Danzhou, Mao, Zong-Wan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115404/
https://www.ncbi.nlm.nih.gov/pubmed/30158518
http://dx.doi.org/10.1038/s41467-018-05810-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115404/
https://www.ncbi.nlm.nih.gov/pubmed/30158518
http://dx.doi.org/10.1038/s41467-018-05810-4

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