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A common polymorphism of COMT was associated with symptomatic lumbar disc herniation based on a large sample with Chinese Han ancestry

Lumbar disc herniation (LDH) is a common spine disease characterized by a tear in the disc ring and bulges out at the soft portion. COMT is a protein coding gene located at 22q11.21, and its gene product is a major mammalian enzyme involved in the degradation of catecholamines. A total of 2,678 stud...

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Detalles Bibliográficos
Autores principales: Liu, Hongliang, Zhao, Hongmou, Li, Zhong, Xue, Hanzhong, Lu, Jun, Ma, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115408/
https://www.ncbi.nlm.nih.gov/pubmed/30158547
http://dx.doi.org/10.1038/s41598-018-31240-9