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A common polymorphism of COMT was associated with symptomatic lumbar disc herniation based on a large sample with Chinese Han ancestry
Lumbar disc herniation (LDH) is a common spine disease characterized by a tear in the disc ring and bulges out at the soft portion. COMT is a protein coding gene located at 22q11.21, and its gene product is a major mammalian enzyme involved in the degradation of catecholamines. A total of 2,678 stud...
Autores principales: | Liu, Hongliang, Zhao, Hongmou, Li, Zhong, Xue, Hanzhong, Lu, Jun, Ma, Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115408/ https://www.ncbi.nlm.nih.gov/pubmed/30158547 http://dx.doi.org/10.1038/s41598-018-31240-9 |
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