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Schlafen2 mutation in mice causes an osteopetrotic phenotype due to a decrease in the number of osteoclast progenitors

Osteoclasts are the bone resorbing cells that derive from myeloid progenitor cells. Although there have been recent advancements in the ability to identify osteoclast progenitors, very little is known about the molecular mechanisms governing their homeostasis. Here, by analyzing the normalized phylo...

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Detalles Bibliográficos
Autores principales: Omar, Ibrahim, Guterman-Ram, Gali, Rahat, Dolev, Tabach, Yuval, Berger, Michael, Levaot, Noam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115409/
https://www.ncbi.nlm.nih.gov/pubmed/30158544
http://dx.doi.org/10.1038/s41598-018-31428-z