Genetic and animal model analyses reveal the pathogenic role of a novel deletion of RELN in schizophrenia

Reelin protein (RELN), an extracellular matrix protein, plays multiple roles that range from embryonic neuronal migration to spine formation in the adult brain. Results from genetic studies have suggested that RELN is associated with the risk of psychiatric disorders, including schizophrenia (SCZ)....

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Detalles Bibliográficos
Autores principales: Sobue, Akira, Kushima, Itaru, Nagai, Taku, Shan, Wei, Kohno, Takao, Aleksic, Branko, Aoyama, Yuki, Mori, Daisuke, Arioka, Yuko, Kawano, Naoko, Yamamoto, Maeri, Hattori, Mitsuharu, Nabeshima, Toshitaka, Yamada, Kiyofumi, Ozaki, Norio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115412/
https://www.ncbi.nlm.nih.gov/pubmed/30158644
http://dx.doi.org/10.1038/s41598-018-31390-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115412/
https://www.ncbi.nlm.nih.gov/pubmed/30158644
http://dx.doi.org/10.1038/s41598-018-31390-w

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