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Genetic and animal model analyses reveal the pathogenic role of a novel deletion of RELN in schizophrenia
Reelin protein (RELN), an extracellular matrix protein, plays multiple roles that range from embryonic neuronal migration to spine formation in the adult brain. Results from genetic studies have suggested that RELN is associated with the risk of psychiatric disorders, including schizophrenia (SCZ)....
Autores principales: | Sobue, Akira, Kushima, Itaru, Nagai, Taku, Shan, Wei, Kohno, Takao, Aleksic, Branko, Aoyama, Yuki, Mori, Daisuke, Arioka, Yuko, Kawano, Naoko, Yamamoto, Maeri, Hattori, Mitsuharu, Nabeshima, Toshitaka, Yamada, Kiyofumi, Ozaki, Norio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115412/ https://www.ncbi.nlm.nih.gov/pubmed/30158644 http://dx.doi.org/10.1038/s41598-018-31390-w |
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