P38α/JNK signaling restrains erythropoiesis by suppressing Ezh2-mediated epigenetic silencing of Bim

While erythropoietin (EPO) constitutes the major treatment for anemia, a range of anemic disorders remain resistant to EPO treatment. The need for alternative therapeutic strategies requires the identification of mechanisms that physiologically restrain erythropoiesis. Here we show that P38α restrai...

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Detalles Bibliográficos
Autores principales: Hu, Ping, Nebreda, Angel R., Hanenberg, Helmut, Kinnebrew, Garrett H., Ivan, Mircea, Yoder, Mervin C., Filippi, Marie-Dominique, Broxmeyer, Hal E., Kapur, Reuben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115418/
https://www.ncbi.nlm.nih.gov/pubmed/30158520
http://dx.doi.org/10.1038/s41467-018-05955-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115418/
https://www.ncbi.nlm.nih.gov/pubmed/30158520
http://dx.doi.org/10.1038/s41467-018-05955-2

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