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PI3Ka-Akt1-mediated Prdm4 induction in adipose tissue increases energy expenditure, inhibits weight gain, and improves insulin resistance in diet-induced obese mice

Stimulation of white adipose tissue (WAT) browning is considered as a potential approach to treat obesity and metabolic diseases. Our previous studies have shown that phytochemical butein can stimulate WAT browning through induction of Prdm4 in adipocytes. Here, we investigated the effects of butein...

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Detalles Bibliográficos
Autores principales: Song, No-Joon, Chang, Seo-Hyuk, Kim, Suji, Panic, Vanja, Jang, Byung-Hyun, Yun, Ui Jeong, Choi, Jin Hee, Li, Zhen, Park, Ki-Moon, Yoon, Jung-Hoon, Kim, Sunghwan, Yoo, Jae Hyuk, Ling, Jing, Thomas, Kirk, Villanueva, Claudio J., Li, Dean Y., Ahn, Jee-Yin, Ku, Jin-Mo, Park, Kye Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115456/
https://www.ncbi.nlm.nih.gov/pubmed/30158592
http://dx.doi.org/10.1038/s41419-018-0904-3