Full-Profile Pharmacokinetic Study of High Dose Baclofen in Subjects With Alcohol Use Disorder

Baclofen a gamma amino-butyric acid type B (GABA-B) receptor agonist, which has raised some interest for the treatment of alcohol use disorder (AUD), occasionally at dose up to 300 mg/d. We conducted the first full-profile pharmacokinetic study on baclofen in AUD subjects, up to the oral daily dose...

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Detalles Bibliográficos
Autores principales: Simon, Nicolas, Moirand, Romain, Dematteis, Maurice, Bordet, Régis, Deplanque, Dominique, Rolland, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Psychiatry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115517/
https://www.ncbi.nlm.nih.gov/pubmed/30190685
http://dx.doi.org/10.3389/fpsyt.2018.00385

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115517/
https://www.ncbi.nlm.nih.gov/pubmed/30190685
http://dx.doi.org/10.3389/fpsyt.2018.00385

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