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Programmable one-pot synthesis of heparin pentasaccharides enabling access to regiodefined sulfate derivatives
Heparin (H) and heparan sulfate (HS) belong to the glycosaminoglycan (GAG) family of oligosaccharides, and their sequences and sulfation patterns are known to regulate the functions of various proteins in biological processes. Among these, the 6-O-sulfation of HS/H contributes most significantly to...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Royal Society of Chemistry
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115620/ https://www.ncbi.nlm.nih.gov/pubmed/30310602 http://dx.doi.org/10.1039/c8sc01743c |