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Synergistic formal ring contraction for the enantioselective synthesis of spiropyrazolones

The rapid generation of molecular complexity from simple reactants is a key challenge in organic synthesis. Spiro compounds, underrepresented 3D motifs in chemical libraries, represent a challenge due to the creation of spiro quaternary carbon and the need to control the 3D shape in one step. Herein...

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Detalles Bibliográficos
Autores principales: Meazza, Marta, Kamlar, Martin, Jašíková, Lucie, Formánek, Bedřich, Mazzanti, Andrea, Roithová, Jana, Veselý, Jan, Rios, Ramon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115638/
https://www.ncbi.nlm.nih.gov/pubmed/30310564
http://dx.doi.org/10.1039/c8sc00913a