Diverse secondary C(sp(3))–H bond functionalization via site-selective trifluoroacetoxylation of aliphatic amines

We describe a coinage-metal-catalyzed site-selective oxidation of secondary C(sp(3))–H bonds for aliphatic amine substrates. Broad amine scope, good functional compatibility and late-stage diversification are demonstrated with this method. The steric demand of the β-substituents controlled diastereo...

Descripción completa

Detalles Bibliográficos
Autores principales: Tang, Yongzhen, Qin, Yuman, Meng, Dongmei, Li, Chaoqun, Wei, Junfa, Yang, Mingyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115674/
https://www.ncbi.nlm.nih.gov/pubmed/30310565
http://dx.doi.org/10.1039/c8sc01788c

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115674/
https://www.ncbi.nlm.nih.gov/pubmed/30310565
http://dx.doi.org/10.1039/c8sc01788c

Ejemplares similares