Cargando…
Designer Approaches for G Protein–Coupled Receptor Modulation for Cardiovascular Disease
The new horizon for cardiac therapy may lie beneath the surface, with the downstream mediators of G protein–coupled receptor (GPCR) activity. Targeted approaches have shown that receptor activation may be biased toward signaling through G proteins or through GPCR kinases (GRKs) and β-arrestins, with...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115700/ https://www.ncbi.nlm.nih.gov/pubmed/30175279 http://dx.doi.org/10.1016/j.jacbts.2017.12.002 |