Designer Approaches for G Protein–Coupled Receptor Modulation for Cardiovascular Disease

The new horizon for cardiac therapy may lie beneath the surface, with the downstream mediators of G protein–coupled receptor (GPCR) activity. Targeted approaches have shown that receptor activation may be biased toward signaling through G proteins or through GPCR kinases (GRKs) and β-arrestins, with...

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Detalles Bibliográficos
Autores principales: Grisanti, Laurel A., Schumacher, Sarah M., Tilley, Douglas G., Koch, Walter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
STATE-OF-THE-ART REVIEW
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115700/
https://www.ncbi.nlm.nih.gov/pubmed/30175279
http://dx.doi.org/10.1016/j.jacbts.2017.12.002

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