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Association of NF-κB and AP-1 with MMP-9 Overexpression in 2-Chloroethanol Exposed Rat Astrocytes

Subacute poisoning of 1,2-dichloroethane (1,2-DCE) has become a serious occupational problem in China, and brain edema is its main pathological consequence, but little is known about the underlying mechanisms. As the metabolite of 1,2-DCE, 2-chloroethanol (2-CE) is more reactive, and might play an i...

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Detalles Bibliográficos
Autores principales: Wang, Tong, Jin, Xiaoxia, Liao, Yingjun, Sun, Qi, Luo, Chaohong, Wang, Gaoyang, Zhao, Fenghong, Jin, Yaping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115792/
https://www.ncbi.nlm.nih.gov/pubmed/30087244
http://dx.doi.org/10.3390/cells7080096