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Pharmacokinetic Properties of the Nephrotoxin Orellanine in Rats

Orellanine is a nephrotoxin found in mushrooms of the Cortinarius family. Accidental intake of this substance may cause renal failure. Orellanine is specific for proximal tubular cells and could, therefore, potentially be used as treatment for metastatic renal cancer, which originates from these cel...

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Detalles Bibliográficos
Autores principales: Najar, Deman, Haraldsson, Börje, Thorsell, Annika, Sihlbom, Carina, Nyström, Jenny, Ebefors, Kerstin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116018/
https://www.ncbi.nlm.nih.gov/pubmed/30126099
http://dx.doi.org/10.3390/toxins10080333