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Pharmacokinetic Properties of the Nephrotoxin Orellanine in Rats
Orellanine is a nephrotoxin found in mushrooms of the Cortinarius family. Accidental intake of this substance may cause renal failure. Orellanine is specific for proximal tubular cells and could, therefore, potentially be used as treatment for metastatic renal cancer, which originates from these cel...
Autores principales: | Najar, Deman, Haraldsson, Börje, Thorsell, Annika, Sihlbom, Carina, Nyström, Jenny, Ebefors, Kerstin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116018/ https://www.ncbi.nlm.nih.gov/pubmed/30126099 http://dx.doi.org/10.3390/toxins10080333 |
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