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TGF-βRII Knock-down in Pancreatic Cancer Cells Promotes Tumor Growth and Gemcitabine Resistance. Importance of STAT3 Phosphorylation on S727

Pancreatic adenocarcinoma (PDAC) is one of the most deadly cancers in the Western world because of a lack of early diagnostic markers and efficient therapeutics. At the time of diagnosis, more than 80% of patients have metastasis or locally advanced cancer and are therefore not eligible for surgical...

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Detalles Bibliográficos
Autores principales: Drubay, Vincent, Skrypek, Nicolas, Cordiez, Lucie, Vasseur, Romain, Schulz, Céline, Boukrout, Nihad, Duchêne, Belinda, Coppin, Lucie, Van Seuningen, Isabelle, Jonckheere, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116183/
https://www.ncbi.nlm.nih.gov/pubmed/30065235
http://dx.doi.org/10.3390/cancers10080254