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Effects of Vitamin K(2) on the Expression of Genes Involved in Bile Acid Synthesis and Glucose Homeostasis in Mice with Humanized PXR

Pregnane X receptor (PXR) is a nuclear receptor activated by various compounds, including prescribed drugs and dietary ingredients. Ligand-specific activation of PXR alters drug metabolism and affects many other physiological conditions. Species-specific ligand preference is a considerable challenge...

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Detalles Bibliográficos
Autores principales: Sultana, Halima, Watanabe, Kimika, Rana, Md Masud, Takashima, Rie, Ohashi, Ai, Komai, Michio, Shirakawa, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116188/
https://www.ncbi.nlm.nih.gov/pubmed/30060524
http://dx.doi.org/10.3390/nu10080982