Cargando…

The Precision Control of Autophagic Flux and Vesicle Dynamics—A Micropattern Approach

Autophagy failure is implicated in age-related human disease. A decrease in the rate of protein degradation through the entire autophagy pathway, i.e., autophagic flux, has been associated with the onset of cellular proteotoxity and cell death. Although the precision control of autophagy as a pharma...

Descripción completa

Detalles Bibliográficos
Autores principales: du Toit, André, De Wet, Sholto, Hofmeyr, Jan-Hendrik S., Müller-Nedebock, Kristian K., Loos, Ben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116198/
https://www.ncbi.nlm.nih.gov/pubmed/30081508
http://dx.doi.org/10.3390/cells7080094