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The Autism-Related Protein PX-RICS Mediates GABAergic Synaptic Plasticity in Hippocampal Neurons and Emotional Learning in Mice

GABAergic dysfunction underlies many neurodevelopmental and psychiatric disorders. GABAergic synapses exhibit several forms of plasticity at both pre- and postsynaptic levels. NMDA receptor (NMDAR)–dependent inhibitory long-term potentiation (iLTP) at GABAergic postsynapses requires an increase in s...

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Detalles Bibliográficos
Autores principales: Nakamura, Tsutomu, Sakaue, Fumika, Nasu-Nishimura, Yukiko, Takeda, Yasuko, Matsuura, Ken, Akiyama, Tetsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116350/
https://www.ncbi.nlm.nih.gov/pubmed/30045817
http://dx.doi.org/10.1016/j.ebiom.2018.07.011