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A Quantitative Evaluation of MIRU-VNTR Typing Against Whole-Genome Sequencing for Identifying Mycobacterium tuberculosis Transmission: A Prospective Observational Cohort Study

BACKGROUND: Mycobacterial Interspersed Repetitive Unit-Variable Number Tandem Repeat (MIRU-VNTR) typing is widely used in high-income countries to determine Mycobacterium tuberculosis relatedness. Whole-genome sequencing (WGS) is known to deliver greater specificity, but no quantitative prospective...

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Detalles Bibliográficos
Autores principales: Wyllie, David H., Davidson, Jennifer A., Grace Smith, E., Rathod, Priti, Crook, Derrick W., Peto, Tim E.A., Robinson, Esther, Walker, Tim, Campbell, Colin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116353/
https://www.ncbi.nlm.nih.gov/pubmed/30077721
http://dx.doi.org/10.1016/j.ebiom.2018.07.019