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Temperature responses of mutation rate and mutational spectrum in an Escherichia coli strain and the correlation with metabolic rate

BACKGROUND: Temperature is a major determinant of spontaneous mutation, but the precise mode, and the underlying mechanisms, of the temperature influences remain less clear. Here we used a mutation accumulation approach combined with whole-genome sequencing to investigate the temperature dependence...

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Detalles Bibliográficos
Autores principales: Chu, Xiao-Lin, Zhang, Bo-Wen, Zhang, Quan-Guo, Zhu, Bi-Ru, Lin, Kui, Zhang, Da-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116381/
https://www.ncbi.nlm.nih.gov/pubmed/30157765
http://dx.doi.org/10.1186/s12862-018-1252-8