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Temperature responses of mutation rate and mutational spectrum in an Escherichia coli strain and the correlation with metabolic rate
BACKGROUND: Temperature is a major determinant of spontaneous mutation, but the precise mode, and the underlying mechanisms, of the temperature influences remain less clear. Here we used a mutation accumulation approach combined with whole-genome sequencing to investigate the temperature dependence...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116381/ https://www.ncbi.nlm.nih.gov/pubmed/30157765 http://dx.doi.org/10.1186/s12862-018-1252-8 |