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Differentiation and transplantation of human induced pluripotent stem cell-derived otic epithelial progenitors in mouse cochlea

BACKGROUND: Inner ear hair cells as mechanoreceptors are extremely important for hearing. Defects in hair cells are a major cause of deafness. Induced pluripotent stem cells (iPSCs) are promising for regenerating inner ear hair cells and treating hearing loss. Here, we investigated migration, differ...

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Detalles Bibliográficos
Autores principales: Chen, Jianling, Hong, Fanfan, Zhang, Cui, Li, Liang, Wang, Cuicui, Shi, Haosong, Fu, Yong, Wang, Jinfu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116394/
https://www.ncbi.nlm.nih.gov/pubmed/30157937
http://dx.doi.org/10.1186/s13287-018-0967-1