Cargando…
Differentiation and transplantation of human induced pluripotent stem cell-derived otic epithelial progenitors in mouse cochlea
BACKGROUND: Inner ear hair cells as mechanoreceptors are extremely important for hearing. Defects in hair cells are a major cause of deafness. Induced pluripotent stem cells (iPSCs) are promising for regenerating inner ear hair cells and treating hearing loss. Here, we investigated migration, differ...
Autores principales: | Chen, Jianling, Hong, Fanfan, Zhang, Cui, Li, Liang, Wang, Cuicui, Shi, Haosong, Fu, Yong, Wang, Jinfu |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116394/ https://www.ncbi.nlm.nih.gov/pubmed/30157937 http://dx.doi.org/10.1186/s13287-018-0967-1 |
Ejemplares similares
-
Enriched Differentiation of Human Otic Sensory Progenitor Cells Derived From Induced Pluripotent Stem Cells
por: Lahlou, Hanae, et al.
Publicado: (2018) -
Regeneration of Hair Cells from Endogenous Otic Progenitors in the Adult Mammalian Cochlea: Understanding Its Origins and Future Directions
por: Smith-Cortinez, Natalia, et al.
Publicado: (2023) -
Stepwise Induction of Inner Ear Hair Cells From Mouse Embryonic Fibroblasts via Mesenchymal- to-Epithelial Transition and Formation of Otic Epithelial Cells
por: Yang, Qiong, et al.
Publicado: (2021) -
Generation of human otic neuronal organoids using pluripotent stem cells
por: Sun, Gaoying, et al.
Publicado: (2023) -
Greater epithelial ridge cells are the principal organoid-forming progenitors of the mouse cochlea
por: Kubota, Marie, et al.
Publicado: (2021)