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β-Catenin Regulation in Sporadic Colorectal Carcinogenesis: Not as Simple as APC

BACKGROUND: The wnt/APC/β-catenin pathway is a critical initiator in colorectal carcinogenesis in both hereditary and sporadic colorectal cancer (CRC). The progression of this process remains incompletely understood, although inflammation is pivotal. Drivers of inflammation are elevated in malignant...

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Detalles Bibliográficos
Autores principales: Fredericks, Ernst, Dealtry, Gill, Roux, Saartjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116401/
https://www.ncbi.nlm.nih.gov/pubmed/30186819
http://dx.doi.org/10.1155/2018/4379673