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Decreased Hepcidin Levels Are Associated with Low Steady-state Hemoglobin in Children With Sickle Cell Disease in Tanzania

BACKGROUND: The contribution of hepcidin as a regulator of iron metabolism & erythropoiesis on the severity of anemia in sickle cell disease (SCD) remains poorly characterized, especially in Sub-Saharan African populations. The aims of the study were to determine if hepcidin is associated with s...

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Detalles Bibliográficos
Autores principales: Lee, Nathaniel, Makani, Julie, Tluway, Furahini, Makubi, Abel, Armitage, Andrew E., Pasricha, Sant-Rayn, Drakesmith, Hal, Prentice, Andrew M., Cox, Sharon E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116423/
https://www.ncbi.nlm.nih.gov/pubmed/30056060
http://dx.doi.org/10.1016/j.ebiom.2018.07.024