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Retrospective cohort study comparing the risk of severe hepatotoxicity in hospitalized patients treated with echinocandins for invasive candidiasis in the presence of confounding by indication

BACKGROUND: To compare the risk of severe hepatotoxicity with anidulafungin versus caspofungin and micafungin in hospitalized adults. METHODS: This retrospective cohort study combined data from two large US- based hospital electronic medical record databases. Severe hepatotoxicity was a Grade ≥ 3 li...

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Detalles Bibliográficos
Autores principales: Vekeman, Francis, Weiss, Lisa, Aram, Jalal, Ionescu-Ittu, Raluca, Moosavi, Shahrzad, Xiao, Yongling, Cheng, Wendy Y., Bhak, Rachel H., Tawadrous, Margaret, Capparella, M. Rita, Montravers, Philippe, Duh, Mei Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116432/
https://www.ncbi.nlm.nih.gov/pubmed/30157797
http://dx.doi.org/10.1186/s12879-018-3333-0