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Cytokines induced killer cells produced in good manufacturing practices conditions: identification of the most advantageous and safest expansion method in terms of viability, cellular growth and identity

BACKGROUND: Cytokine-induced killer (CIK) cells are a very promising cell population raising growing interest in the field of cellular antitumor therapy. The aim of our study was to validate the most advantageous expansion method for this advanced therapy medicinal product (ATMP) and to translate it...

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Detalles Bibliográficos
Autores principales: Sara, Castiglia, Aloe, Adamini, Deborah, Rustichelli, Laura, Castello, Katia, Mareschi, Giuseppe, Pinnetta, Marco, Leone, Alessandra, Mandese, Ivana, Ferrero, Giulia, Mesiano, Franca, Fagioli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116438/
https://www.ncbi.nlm.nih.gov/pubmed/30157948
http://dx.doi.org/10.1186/s12967-018-1613-5