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In vivo evolution of drug-resistant Mycobacterium tuberculosis in patients during long-term treatment

BACKGROUND: In the current scenario, the drug-resistant tuberculosis is a significant challenge in the control of tuberculosis worldwide. In order to investigate the in vivo evolution of drug-resistant M. tuberculosis, the present study envisaged sequencing of the draft genomes of 18 serial isolates...

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Detalles Bibliográficos
Autores principales: Xu, Yuhui, Liu, Fei, Chen, Suting, Wu, Jiannan, Hu, Yongfei, Zhu, Baoli, Sun, Zhaogang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116439/
https://www.ncbi.nlm.nih.gov/pubmed/30157763
http://dx.doi.org/10.1186/s12864-018-5010-5