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Activation of pro-survival metabolic networks by 1,25(OH)(2)D(3) does not hamper the sensitivity of breast cancer cells to chemotherapeutics

BACKGROUND: We have previously identified 1,25-dihydroxyvitamin D(3) [1,25(OH)(2)D(3)], the bioactive form of vitamin D(3), as a potent regulator of energy-utilization and nutrient-sensing pathways in prostate cancer cells. In the current study, we investigated the effects of 1,25(OH)(2)D(3) on brea...

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Detalles Bibliográficos
Autores principales: Abu el Maaty, Mohamed A., Dabiri, Yasamin, Almouhanna, Fadi, Blagojevic, Biljana, Theobald, Jannick, Büttner, Michael, Wölfl, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116450/
https://www.ncbi.nlm.nih.gov/pubmed/30181873
http://dx.doi.org/10.1186/s40170-018-0183-6