Cargando…

Activation of pro-survival metabolic networks by 1,25(OH)(2)D(3) does not hamper the sensitivity of breast cancer cells to chemotherapeutics

BACKGROUND: We have previously identified 1,25-dihydroxyvitamin D(3) [1,25(OH)(2)D(3)], the bioactive form of vitamin D(3), as a potent regulator of energy-utilization and nutrient-sensing pathways in prostate cancer cells. In the current study, we investigated the effects of 1,25(OH)(2)D(3) on brea...

Descripción completa

Detalles Bibliográficos
Autores principales:	Abu el Maaty, Mohamed A., Dabiri, Yasamin, Almouhanna, Fadi, Blagojevic, Biljana, Theobald, Jannick, Büttner, Michael, Wölfl, Stefan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116450/ https://www.ncbi.nlm.nih.gov/pubmed/30181873 http://dx.doi.org/10.1186/s40170-018-0183-6

Ejemplares similares

Expression of TXNIP in Cancer Cells and Regulation by 1,25(OH)(2)D(3): Is It Really the Vitamin D(3) Upregulated Protein?
por: Abu el Maaty, Mohamed A., et al.
Publicado: (2018)

A Ruthenium(II) N-Heterocyclic Carbene (NHC) Complex with Naphthalimide Ligand Triggers Apoptosis in Colorectal Cancer Cells via Activating the ROS-p38 MAPK Pathway
por: Dabiri, Yasamin, et al.
Publicado: (2018)

Cell Type-Specific Metabolic Response to Amino Acid Starvation Dictates the Role of Sestrin2 in Regulation of mTORC1
por: Blagojevic, Biljana, et al.
Publicado: (2022)

Effects of 1,25(OH)(2)D(3) on Cancer Cells and Potential Applications in Combination with Established and Putative Anti-Cancer Agents
por: Abu el Maaty, Mohamed A., et al.
Publicado: (2017)

Pharmacological activation of pyruvate kinase M2 reprograms glycolysis leading to TXNIP depletion and AMPK activation in breast cancer cells
por: Almouhanna, Fadi, et al.
Publicado: (2021)

p53-Dependent Anti-Proliferative and Pro-Apoptotic Effects of a Gold(I) N-Heterocyclic Carbene (NHC) Complex in Colorectal Cancer Cells
por: Dabiri, Yasamin, et al.
Publicado: (2019)

Association among plasma 1,25(OH)(2)D, ratio of 1,25(OH)(2)D to 25(OH)D, and prostate cancer aggressiveness
por: Ramakrishnan, Swathi, et al.
Publicado: (2019)

In vitro metabolic activation of vitamin D3 by using a multi-compartment microfluidic liver-kidney organ on chip platform
por: Theobald, Jannick, et al.
Publicado: (2019)

Does Sevelamer Hydrochloride (Renagel) Influence 25(Oh)D3 and 1,25(Oh)2D3 Level in Haemodialysis Patients?
por: Strózecki, Pawel, et al.
Publicado: (2005)

Multiple Sclerosis Patients Show Lower Bioavailable 25(OH)D and 1,25(OH)(2)D, but No Difference in Ratio of 25(OH)D/24,25(OH)(2)D and FGF23 Concentrations
por: Vlot, Mariska C, et al.
Publicado: (2019)

Vitamin D and 1,25(OH)(2)D Regulation of T cells
por: Cantorna, Margherita T., et al.
Publicado: (2015)

25(OH)D and 1,25(OH)D vitamin D fails to predict sepsis and mortality in a prospective cohort study
por: Ratzinger, Franz, et al.
Publicado: (2017)

Antidepressants differentially related to 1,25-(OH)(2) vitamin D(3) and 25-(OH) vitamin D(3) in late-life depression
por: Oude Voshaar, R C, et al.
Publicado: (2014)

25(OH)D(3) and 1.25(OH)(2)D(3) inhibits TNF-α expression in human monocyte derived macrophages
por: Rafique, Aisha, et al.
Publicado: (2019)

MON-LB74 The Problem of Measuring 1,25(OH)2 Vitamin D in Patients With High Levels of 25(OH) Vitamin D
por: Vieira, Jose Gilberto, et al.
Publicado: (2020)

Circulatory 25(OH)D and 1,25(OH)(2)D as differential biomarkers between multiple system atrophy and Parkinson's disease patients
por: Ogura, Hiromu, et al.
Publicado: (2021)

25(OH)D-but not 1,25(OH)(2)D–Is an independent risk factor predicting graft loss in stable kidney transplant recipients
por: Zeng, Shufei, et al.
Publicado: (2023)

1,25-Dihydroxyvitamin D(3) (1,25(OH)(2)D(3)) Signaling Capacity and the Epithelial-Mesenchymal Transition in Non-Small Cell Lung Cancer (NSCLC): Implications for Use of 1,25(OH)(2)D(3) in NSCLC Treatment
por: Upadhyay, Santosh Kumar, et al.
Publicado: (2013)

The metabolism of 1,25(OH)(2)D(3) in clinical and experimental kidney disease
por: Turner, Mandy E., et al.
Publicado: (2022)

Effects of 1,25(OH)(2)D(3) and 25(OH)D(3) on C2C12 Myoblast Proliferation, Differentiation, and Myotube Hypertrophy
por: van der Meijden, K., et al.
Publicado: (2016)

Vitamin D as a Novel Regulator of Tumor Metabolism: Insights on Potential Mechanisms and Implications for Anti-Cancer Therapy
por: Abu el Maaty, Mohamed A., et al.
Publicado: (2017)

pVHL-mediated SMAD3 degradation suppresses TGF-β signaling
por: Zhou, Jun, et al.
Publicado: (2021)

Vitamin D (1,25(OH)(2)D3) induces α-1-antitrypsin synthesis by CD4(+) T cells, which is required for 1,25(OH)(2)D3-driven IL-10
por: Dimeloe, Sarah, et al.
Publicado: (2019)

Recruitment, augmentation and apoptosis of rat osteoclasts in 1,25-(OH)(2)D(3) response to short-term treatment with 1,25-dihydroxyvitamin D(3)in vivo
por: Miao, Dengshun, et al.
Publicado: (2002)

Anti-Inflammatory Effects of 1,25(OH)2D/Calcitriol in T Cell Immunity: Does Sex Make a Difference?
por: Peruzzu, Daniela, et al.
Publicado: (2022)

1,25(OH)(2)D(3) Promotes the Efficacy of CD28 Costimulation Blockade by Abatacept
por: Gardner, David H., et al.
Publicado: (2015)

1,25(OH)(2)D(3) dependent overt hyperactivity phenotype in klotho-hypomorphic mice
por: Leibrock, Christina B., et al.
Publicado: (2016)

Without 1α-hydroxylation, the gene expression profile of 25(OH)D(3) treatment overlaps deeply with that of 1,25(OH)(2)D(3) in prostate cancer cells
por: Susa, Takao, et al.
Publicado: (2018)

The 25(OH)D3, but Not 1,25(OH)2D3 Levels Are Elevated in IBD Patients Regardless of Vitamin D Supplementation and Do Not Associate with Pain Severity or Frequency
por: Zielińska, Anna, et al.
Publicado: (2021)

Metabolic Advantage of 25(OH)D(3) versus 1,25(OH)(2)D(3) Supplementation in Infantile Nephropathic Cystinosis-Associated Adipose Tissue Browning and Muscle Wasting
por: Zhou, Ping, et al.
Publicado: (2022)

1,25OH-Vitamin D3 and IL-17 Inhibition Modulate Pro-Fibrotic Cytokines Production in Peripheral Blood Mononuclear Cells of Patients with Systemic Sclerosis
por: Corrado, Addolorata, et al.
Publicado: (2022)

The Impact of Estradiol and 1,25(OH)2D3 on Metabolic Syndrome in Middle-Aged Taiwanese Males
por: Cheng, Kai-Hung, et al.
Publicado: (2013)

1,25 (OH)(2)D(3) treatment alters the granulomatous response in M. tuberculosis infected mice
por: Bhatt, Kamlesh, et al.
Publicado: (2016)

In vitro induction effect of 1,25(OH)(2)D(3) on differentiation of hair follicle stem cell into keratinocyte
por: Joulai Veijouyeh, Sanaz, et al.
Publicado: (2017)

1,25(OH)(2)D(3) Protects Liver Fibrosis Through Decreasing the Generation of TH17 Cells
por: Gu, Lei, et al.
Publicado: (2017)

Anaplastic large cell lymphoma, with 1,25(OH)((2))D((3))-mediated hypercalcemia: A case report
por: Mitobe, Masaki, et al.
Publicado: (2019)

Action of 1,25(OH)(2)D(3) on Human Asthmatic Bronchial Fibroblasts: Implications for Airway Remodeling in Asthma
por: Plesa, Maria, et al.
Publicado: (2020)

Additive Effects of VDBP and 1,25(OH)2D3 on the Viability and Apoptosis of Rheumatoid Arthritis Synovial Fibroblasts
por: Zhang, Yeyong, et al.
Publicado: (2021)

Vitamin D and the Ability to Produce 1,25(OH)(2)D Are Critical for Protection from Viral Infection of the Lungs
por: Arora, Juhi, et al.
Publicado: (2022)

Maternal serum retinol, 25(OH)D and 1,25(OH)(2)D concentrations during pregnancy and peak bone mass and trabecular bone score in adult offspring at 26-year follow-up
por: Balasuriya, Chandima N. D., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_ln5lpldo5vcmvnbhhnvkje89fv