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Neuroprotective Activity of Sitagliptin via Reduction of Neuroinflammation beyond the Incretin Effect: Focus on Alzheimer's Disease

Sitagliptin is a member of a class of drugs that inhibit dipeptidyl peptidase (DPP-4). It increases the levels of the active form of incretins such as GLP-1 (glucagon-like peptide-1) or GIP (gastric inhibitory polypeptide) and by their means positively affects glucose metabolism. It is successfully...

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Detalles Bibliográficos
Autores principales: Wiciński, Michał, Wódkiewicz, Eryk, Słupski, Maciej, Walczak, Maciej, Socha, Maciej, Malinowski, Bartosz, Pawlak-Osińska, Katarzyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116461/
https://www.ncbi.nlm.nih.gov/pubmed/30186862
http://dx.doi.org/10.1155/2018/6091014