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Astragaloside IV inhibits lung cancer progression and metastasis by modulating macrophage polarization through AMPK signaling
BACKGROUND: Accumulating evidence suggests that M2-polarized tumor-associated macrophages (TAMs) play an important role in cancer progression and metastasis, making M2 polarization of TAMs an ever more appealing target for therapeutic intervention. Astragaloside IV (AS-IV), a saponin component isola...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116548/ https://www.ncbi.nlm.nih.gov/pubmed/30157903 http://dx.doi.org/10.1186/s13046-018-0878-0 |