Cargando…

Astragaloside IV inhibits lung cancer progression and metastasis by modulating macrophage polarization through AMPK signaling

BACKGROUND: Accumulating evidence suggests that M2-polarized tumor-associated macrophages (TAMs) play an important role in cancer progression and metastasis, making M2 polarization of TAMs an ever more appealing target for therapeutic intervention. Astragaloside IV (AS-IV), a saponin component isola...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Fei, Cui, Wen-Qiang, Wei, Ying, Cui, Jie, Qiu, Jian, Hu, Ling-Li, Gong, Wei-Yi, Dong, Jing-Cheng, Liu, Bao-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116548/
https://www.ncbi.nlm.nih.gov/pubmed/30157903
http://dx.doi.org/10.1186/s13046-018-0878-0