Cargando…

Astragaloside IV inhibits lung cancer progression and metastasis by modulating macrophage polarization through AMPK signaling

BACKGROUND: Accumulating evidence suggests that M2-polarized tumor-associated macrophages (TAMs) play an important role in cancer progression and metastasis, making M2 polarization of TAMs an ever more appealing target for therapeutic intervention. Astragaloside IV (AS-IV), a saponin component isola...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xu, Fei, Cui, Wen-Qiang, Wei, Ying, Cui, Jie, Qiu, Jian, Hu, Ling-Li, Gong, Wei-Yi, Dong, Jing-Cheng, Liu, Bao-Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116548/ https://www.ncbi.nlm.nih.gov/pubmed/30157903 http://dx.doi.org/10.1186/s13046-018-0878-0

Ejemplares similares

Correction: Astragaloside IV inhibits lung cancer progression and metastasis by modulating macrophage polarization through AMPK signaling
por: Xu, Fei, et al.
Publicado: (2023)

Astragaloside IV Alleviates the Experimental DSS-Induced Colitis by Remodeling Macrophage Polarization Through STAT Signaling
por: Tian, Lianlian, et al.
Publicado: (2021)

Research progress on the mechanism of astragaloside IV in the treatment of asthma
por: Yuan, Fanyi, et al.
Publicado: (2023)

Effects of astragaloside IV on the pharmacokinetics of omeprazole in rats
por: Liu, Wei, et al.
Publicado: (2019)

Astragaloside IV alleviates heart failure by modulating Nrf-2
por: Feng, Wenxiao, et al.
Publicado: (2022)

Astragaloside IV ameliorates diabetic nephropathy by modulating the mitochondrial quality control network
por: Liu, Xinhui, et al.
Publicado: (2017)

Anticancer effects and mechanisms of astragaloside-IV
por: Zhou, Liangxing, et al.
Publicado: (2022)

Astragaloside IV inhibits astrocyte senescence: implication in Parkinson’s disease
por: Xia, Mei-Ling, et al.
Publicado: (2020)

Influence of astragaloside IV on pharmacokinetics of triptolide in rats and its potential mechanism
por: Gao, Jian, et al.
Publicado: (2020)

Astragaloside IV Attenuates the Myocardial Injury Caused by Adriamycin by Inhibiting Autophagy
por: Luo, Li-Fei, et al.
Publicado: (2021)

Astragaloside IV alleviates liver injury in type 2 diabetes due to promotion of AMPK/mTOR-mediated autophagy
por: Zhu, Yunfeng, et al.
Publicado: (2021)

Effects of Astragaloside IV on heart failure in rats
por: Zhao, Zhuanyou, et al.
Publicado: (2009)

Astragaloside IV, as a potential anticancer agent
por: Xia, Dongqin, et al.
Publicado: (2023)

Pharmacological Effects of Astragaloside IV: A Review
por: Liang, Yutong, et al.
Publicado: (2023)

Untapping the Potential of Astragaloside IV in the Battle Against Respiratory Diseases
por: Tan, Junlan, et al.
Publicado: (2023)

Astragaloside IV Protects Detrusor from Partial Bladder Outlet Obstruction-Induced Oxidative Stress by Activating Mitophagy through AMPK-ULK1 Pathway
por: Zhu, Xiaoyu, et al.
Publicado: (2022)

Astragaloside IV Improves Bleomycin-Induced Pulmonary Fibrosis in Rats by Attenuating Extracellular Matrix Deposition
por: Li, Liu-Cheng, et al.
Publicado: (2017)

Regulatory Effects of Astragaloside IV on Hyperglycemia-Induced Mitophagy in Schwann Cells
por: Wei, Xiaoyi, et al.
Publicado: (2022)

Research Progress on the Ability of Astragaloside IV to Protect the Brain Against Ischemia-Reperfusion Injury
por: Kang, Xianhui, et al.
Publicado: (2021)

The Astragaloside IV Derivative LS-102 Ameliorates Obesity-Related Nephropathy
por: Li, Ziyu, et al.
Publicado: (2022)

Gastroprotective Effects of Astragaloside IV against Acute Gastric Lesion in Rats
por: Mao, Shuai, et al.
Publicado: (2016)

Astragalosidic Acid: A New Water-Soluble Derivative of Astragaloside IV Prepared Using Remarkably Simple TEMPO-Mediated Oxidation
por: Qing, Lin-Sen, et al.
Publicado: (2017)

A Preclinical Systematic Review and Meta-Analysis of Astragaloside IV for Myocardial Ischemia/Reperfusion Injury
por: Zheng, Qun, et al.
Publicado: (2018)

The mechanism of astragaloside IV promoting sciatic nerve regeneration
por: Zhang, Xiaohong, et al.
Publicado: (2013)

Astragaloside IV: An Effective Drug for the Treatment of Cardiovascular Diseases
por: Tan, Yu-Qing, et al.
Publicado: (2020)

Molecular mechanisms of astragaloside-IV in cancer therapy (Review)
por: Chen, Tianqi, et al.
Publicado: (2021)

Roles and Mechanisms of Astragaloside IV in Combating Neuronal Aging
por: Zaman, Qumar, et al.
Publicado: (2022)

Transcriptomic Analysis Reveals the Protection of Astragaloside IV against Diabetic Nephropathy by Modulating Inflammation
por: Zhang, Yudi, et al.
Publicado: (2020)

Astragaloside IV alleviates placental oxidative stress and inflammation in GDM mice
por: Zhou, Ling, et al.
Publicado: (2020)

Astragaloside IV modulates TGF‐β1‐dependent epithelial‐mesenchymal transition in bleomycin‐induced pulmonary fibrosis
por: Qian, Weibin, et al.
Publicado: (2018)

Research on the interaction of astragaloside IV and calycosin in Astragalus membranaceus with HMGB1
por: Ye, Junyi, et al.
Publicado: (2023)

Astragaloside IV attenuates hypoxia-induced pulmonary vascular remodeling via the Notch signaling pathway
por: Yao, Jiamei, et al.
Publicado: (2021)

Astragaloside IV attenuates hypoxia-induced pulmonary vascular remodeling via the Notch signaling pathway
por: Yao, Jiamei, et al.
Publicado: (2022)

Astragaloside IV Inhibits NF-κB Activation and Inflammatory Gene Expression in LPS-Treated Mice
por: Zhang, Wei-Jian, et al.
Publicado: (2015)

Astragaloside IV inhibits pathological functions of gastric cancer-associated fibroblasts
por: Wang, Zhen-Fei, et al.
Publicado: (2017)

Astragaloside IV Inhibits the Proliferation of Human Uterine Leiomyomas by Targeting IDO1
por: Qiu, Tiantian, et al.
Publicado: (2022)

Astragaloside IV Ameliorates Isoprenaline-Induced Cardiac Fibrosis in Mice via Modulating Gut Microbiota and Fecal Metabolites
por: Du, Xu-Qin, et al.
Publicado: (2022)

The Mechanism Actions of Astragaloside IV Prevents the Progression of Hypertensive Heart Disease Based on Network Pharmacology and Experimental Pharmacology
por: Jing, Haoran, et al.
Publicado: (2021)

Astragaloside IV ameliorates allergic inflammation by inhibiting key initiating factors in the initial stage of sensitization
por: Bao, Kai-fan, et al.
Publicado: (2016)

Astragaloside IV Ameliorates Airway Inflammation in an Established Murine Model of Asthma by Inhibiting the mTORC1 Signaling Pathway
por: Jin, Hualiang, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_a4g6qvs22t6mn1vap1rvtou1ho