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Short term optical defocus perturbs normal developmental shifts in retina/RPE protein abundance

BACKGROUND: Myopia (short-sightedness) affects approximately 1.4 billion people worldwide, and prevalence is increasing. Animal models induced by defocusing lenses show striking similarity with human myopia in terms of morphology and the implicated genetic pathways. Less is known about proteome chan...

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Detalles Bibliográficos
Autores principales: Riddell, Nina, Faou, Pierre, Crewther, Sheila G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116556/
https://www.ncbi.nlm.nih.gov/pubmed/30157773
http://dx.doi.org/10.1186/s12861-018-0177-1