RUNX1 upregulation via disruption of long-range transcriptional control by a novel t(5;21)(q13;q22) translocation in acute myeloid leukemia

RUNX1 encodes a Runt-related transcription factor that is critical for hematopoiesis. In this study, through a combinatorial molecular approach, we characterized a novel t(5;21)(q13;q22) translocation involving RUNX1 that was acquired during the progression of myelodysplastic syndrome to acute myelo...

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Detalles Bibliográficos
Autores principales: Cheng, Chi-Keung, Wong, Terry H. Y., Wan, Thomas S. K., Wang, Angela Z., Chan, Natalie P. H., Chan, Nelson C. N., Li, Chi-Kong, Ng, Margaret H. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116564/
https://www.ncbi.nlm.nih.gov/pubmed/30157851
http://dx.doi.org/10.1186/s12943-018-0881-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116564/
https://www.ncbi.nlm.nih.gov/pubmed/30157851
http://dx.doi.org/10.1186/s12943-018-0881-2

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