Osteogenic differentiation of fibroblast-like synovial cells in rheumatoid arthritis is induced by microRNA-218 through a ROBO/Slit pathway

BACKGROUND: Fibroblast-like synovial cells (FLS) have multilineage differentiation potential including osteoblasts. We aimed to investigate the role of microRNAs during the osteogenic differentiation of rheumatoid arthritis (RA)-FLS. METHODS: RA-FLS were differentiated in osteogenic medium for 21 da...

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Detalles Bibliográficos
Autores principales: Iwamoto, Naoki, Fukui, Shoichi, Takatani, Ayuko, Shimizu, Toshimasa, Umeda, Masataka, Nishino, Ayako, Igawa, Takashi, Koga, Tomohiro, Kawashiri, Shin-ya, Ichinose, Kunihiro, Tmai, Mami, Nakamura, Hideki, Origuchi, Tomoki, Chiba, Ko, Osaki, Makoto, Jüngel, Astrid, Gay, Steffen, Kawakami, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116572/
https://www.ncbi.nlm.nih.gov/pubmed/30157923
http://dx.doi.org/10.1186/s13075-018-1703-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116572/
https://www.ncbi.nlm.nih.gov/pubmed/30157923
http://dx.doi.org/10.1186/s13075-018-1703-z

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