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Stepwise modifications of genetic parts reinforce the secretory production of nattokinase in Bacillus subtilis
Nattokinase (NK) is an important serine‐protease with direct fibrinolytic activity involving the prevention of cardiovascular disease as an antithrombotic agent. Dozens of studies have focused on the characterization of intrinsic novel promoters and signal peptides to the secretory production of rec...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116739/ https://www.ncbi.nlm.nih.gov/pubmed/29984489 http://dx.doi.org/10.1111/1751-7915.13298 |