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Stepwise modifications of genetic parts reinforce the secretory production of nattokinase in Bacillus subtilis

Nattokinase (NK) is an important serine‐protease with direct fibrinolytic activity involving the prevention of cardiovascular disease as an antithrombotic agent. Dozens of studies have focused on the characterization of intrinsic novel promoters and signal peptides to the secretory production of rec...

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Detalles Bibliográficos
Autores principales: Cui, Wenjing, Suo, Feiya, Cheng, Jintao, Han, Laichuang, Hao, Wenliang, Guo, Junling, Zhou, Zhemin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116739/
https://www.ncbi.nlm.nih.gov/pubmed/29984489
http://dx.doi.org/10.1111/1751-7915.13298