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Carvedilol Prevents Redox Inactivation of Cardiomyocyte Β(1)-Adrenergic Receptors

The mechanism that leads to a decrease in β(1)-adrenergic receptor (β(1)AR) expression in the failing heart remains uncertain. This study shows that cardiomyocyte β(1)AR expression and isoproterenol responsiveness decrease in response to oxidative stress. Studies of mechanisms show that the redox-de...

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Detalles Bibliográficos
Autores principales: Park, Misun, Steinberg, Susan F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116783/
https://www.ncbi.nlm.nih.gov/pubmed/30175276
http://dx.doi.org/10.1016/j.jacbts.2018.06.002