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γ2 GABA(A)R Trafficking and the Consequences of Human Genetic Variation
GABA type A receptors (GABA(A)Rs) mediate the majority of fast inhibitory neurotransmission in the central nervous system (CNS). Most prevalent as heteropentamers composed of two α, two β, and a γ2 subunit, these ligand-gated ionotropic chloride channels are capable of extensive genetic diversity (α...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116786/ https://www.ncbi.nlm.nih.gov/pubmed/30190672 http://dx.doi.org/10.3389/fncel.2018.00265 |