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γ2 GABA(A)R Trafficking and the Consequences of Human Genetic Variation

GABA type A receptors (GABA(A)Rs) mediate the majority of fast inhibitory neurotransmission in the central nervous system (CNS). Most prevalent as heteropentamers composed of two α, two β, and a γ2 subunit, these ligand-gated ionotropic chloride channels are capable of extensive genetic diversity (α...

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Detalles Bibliográficos
Autores principales:	Lorenz-Guertin, Joshua M., Bambino, Matthew J., Jacob, Tija C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116786/ https://www.ncbi.nlm.nih.gov/pubmed/30190672 http://dx.doi.org/10.3389/fncel.2018.00265

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