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Loss of Regulator of G-Protein Signaling 5 Leads to Neurovascular Protection in Stroke

BACKGROUND AND PURPOSE—: In ischemic stroke, breakdown of the blood-brain barrier (BBB) aggravates brain damage. Pericyte detachment contributes to BBB disruption and neurovascular dysfunction, but little is known about its regulation in stroke. Here, we investigated how loss of RGS5 (regulator of G...

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Detalles Bibliográficos
Autores principales: Özen, Ilknur, Roth, Michaela, Barbariga, Marco, Gaceb, Abderahim, Deierborg, Tomas, Genové, Guillem, Paul, Gesine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116795/
https://www.ncbi.nlm.nih.gov/pubmed/30354999
http://dx.doi.org/10.1161/STROKEAHA.118.020124